This handbook is written and used by the UCSF medicine residents and has need-to-know clinical info on outpatient topics with concise sections on evaluation, management, and “when to refer”. With the AgileMD version (accessible even without an internet connection), you can search content quickly, link to calculators, view images, and jump to PubMed references. Use this before or after seeing any patient with a general medicine clinic problem (E.g. AFib, CAD, DM, Hyperthyroid, Women’s Health, Headache, Cough, Diarrhea, etc). This handbook is useful in both the outpatient and inpatient settings.